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An ELCWP Phase III Trial Comparing Ifosfamide and Cisplatin Regimens in Advanced NSCLC.

par Berghmans, Thierry ;Lafitte, Jean-Jacques;Scherpereel, Arnaud;Paesmans, Marianne ;Lecomte, Jacques;Marco, Vicente Giner;Meert, Anne-Pascale ;Leclercq, Nathalie ;Sculier, Jean-Paul ;European Lung Cancer Working Party,
Référence Anticancer research, 33, 12, page (5477-5482)
Publication Publié, 2013-12

Article révisé par les pairs

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Résumé :

Aim: While meta-analyses and clinical trials show improved survival in advanced NSCLC treated with platinum-containing chemotherapy, there are few data concerning front-line platinum-free ifosfamide-based regimens. We aimed to compare cisplatin-based chemotherapy to ifosfamide-gemcitabine (IG) with pre-defined second-line docetaxel.