Article révisé par les pairs
Résumé : The high prevalence (10 to 25%) of blood eosinophilia in patients on maintenance hemodialysis is well established. Because esosinophils are considered to modulate local immediate hypersensitivity reaction, dialysis eosinophilia could be a manifestation of an allergic response to hemodialysis-specific antigen exposure. Among many substances that may involve hypersensitivity in hemodialysis, cuprophane membranes have been implicated. We investigated the possible role of the dialysis membrane in this syndrome by switching hemodialysis patients with persistent eosinophilia from their usual cellulose membranes to polyacrylonitrile membranes.