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Process for the preparation of levetiracetam

par Futagawa, Tooru;Canvat, Jean-Pierre;Cavoy, Emile;Deleers, Michel ;Duchêne, Gaspard;Hamende, Michel ;Zimmermann, Vincent
Publication Publié, 2000-08-22

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Résumé :

Levetiracetam is prepared by optical resolution of etiracetam by means of preparative high performance liquid chromatography or continuous simulated moving bed chromatographic system using silica gel supporting amylose tris(3,5-dimethylphenylcarbamate) as a packing material.