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Thrombin generation in children with sickle cell disease: relationship with age, hemolysis, transcranial doppler velocity, and hydroxyurea treatment.

par Noubouossie, Denis C F;Lê, Phu Quoc ;Rozen, Laurence ;Ziereisen, France ;Willems, Dominique ;Demulder, Anne ;Ferster, Alina
Référence European journal of haematology, 91, 1, page (46-54)
Publication Publié, 2013-07

Article révisé par les pairs

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Résumé :

Increased thrombin generation (TG) was described in sickle cell disease (SCD) children. The aim of this study was to characterize TG at the individual level and assess its relationship with age, hemolysis, transcranial Doppler velocity (TCD), and hydroxyurea treatment.