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A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes.

par Fumagalli, Debora ;Gavin, Patrick G;Taniyama, Yusuke;Kim, Seung Il;Choi, Hyun Joo;Paik, Soonmyung;Pogue-Geile, Katherine L
Référence BMC cancer, 10, page (101)
Publication Publié, 2010

Article révisé par les pairs

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Résumé :

An increasing number of studies show that genetic markers can aid in refining prognostic information and predicting the benefit from systemic therapy. Our goal was to develop a high throughput, cost-effective and simple methodology for the detection of clinically relevant hot spot mutations in colon cancer.