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Therapeutic potential of CB2 targeting in multiple sclerosis.

par Docagne, Fabian;Mestre, Leyre;Loría, Frida;Hernangomez Herrero, Miriam ;Correa, Fernando;Guaza, Carmen
Référence Expert opinion on therapeutic targets, 12, 2, page (185-195)
Publication Publié, 2008-02

Article révisé par les pairs

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Résumé :

Cannabinoids have been shown to exert beneficial actions in different animal models of multiple sclerosis (MS). However, the use of cannabinoids compounds in human therapy is greatly limited by their psychoactivity. Thus, new hopes in MS therapy have arisen from the evidence for a cannabinoid receptor, termed CB2, which is devoid of psychoactive effects in animal models.