par El Kenz, Hanane ;Corazza, Francis ;Van Der Linden, Philippe ;Chabab, Samira ;Vandenvelde, Christian
Référence Transfusion and apheresis science
Publication Publié, 2013-05
Référence Transfusion and apheresis science
Publication Publié, 2013-05
Article révisé par les pairs
Résumé : | Prevention of transfusion-associated graft versus host disease (TA-GVHD) by gamma irradiation is known to induce increased K+ in supernatant of packed red blood cells (PRBCs) stored in CPDA-1 and SAGM conservative solutions. However, no data exist for PRBCs in AS-3 medium which is considered safe for neonatal transfusion. We evaluated haemolysis and K+ release from irradiated AS-3 PRBCs and compared our results with reported data for SAGM and CPDA-1 PRBCs. Our results indicate that irradiated PRBCs stored in AS-3 after more than 7days post-irradiation should not be used in massive and/or rapidly infused transfusions in neonates and infants. |