Titre:
  • Frailty in old age is associated with decreased interleukin-12/23 production in response to toll-like receptor ligation.
Auteur:Compte, Nathalie; Zouaoui Boudjeltia, Karim; Vanhaeverbeek, Michel; De Breucker, Sandra; Tassignon, Joël; Trelcat, Anne; Pepersack, Thierry; Goriely, Stanislas
Informations sur la publication:PloS one, 8, 6, page (e65325)
Statut de publication:Publié, 2013
Sujet CREF:Immunologie
MeSH keywords:Adult
Aged
Aged, 80 and over
Cells, Cultured
Dendritic Cells -- immunology -- metabolism
Female
Frail Elderly
Humans
Imidazoles -- pharmacology
Immunity, Innate
Intercellular Adhesion Molecule-1 -- metabolism
Interleukin-12 -- biosynthesis
Interleukin-23 -- biosynthesis
Ligands
Lipopolysaccharides -- pharmacology
Male
Middle Aged
Nutritional Status -- immunology
Signal Transduction
Toll-Like Receptors -- agonists -- metabolism
Young Adult
Note générale:Journal Article
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:1932-6203
info:doi/10.1371/journal.pone.0065325
info:pii/PONE-D-12-38466
info:scp/84878758157
info:pmid/23755218
PMC3673922