Titre:
  • Effects of denosumab in patients with bone metastases with and without previous bisphosphonate exposure.
Auteur:Body, Jean-Jacques; Lipton, Allan; Gralow, Julie; Steger, Guenther G; Gao, Guozhi M.; Yeh, Howard; Fizazi, Karim
Informations sur la publication:Journal of bone and mineral research, 25, 3, page (440-446)
Statut de publication:Publié, 2010-03
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Bisphosphonates
Bone turnover markers
Clinical trials
Novel entities
Osteoclasts
MeSH keywords:Antibodies, Monoclonal -- administration & dosage -- therapeutic use
Antibodies, Monoclonal, Humanized
Biological Markers -- blood -- metabolism
Bone Density Conservation Agents -- therapeutic use
Bone Neoplasms -- drug therapy -- physiopathology -- secondary
Bone and Bones -- metabolism
Diphosphonates -- administration & dosage -- therapeutic use
Female
Humans
Injections, Subcutaneous
Male
Middle Aged
Neoplasms -- drug therapy -- physiopathology
RANK Ligand -- administration & dosage -- therapeutic use
Note générale:Clinical Trial, Phase II
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
FLWIN
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0884-0431
info:doi/10.1359/jbmr.090810
info:scp/77953438942
info:pmid/19653815