Titre:
  • Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones.
Auteur:Maes, Christa; Goossens, Steven; Bartunkova, Sonia; Drogat, Benjamin; Coenegrachts, Lieve; Stockmans, Ingrid; Moermans, Karen; Nyabi, Omar; Haigh, Katharina; Naessens, Michael; Haenebalcke, Lieven; Tuckermann, Jan P; Tjwa, Marc; Carmeliet, Peter; Mandic, Vice; David, Jean-Pierre; Behrens, Axel; Nagy, Andras; Carmeliet, Geert; Haigh, Jody J
Informations sur la publication:EMBO journal, 29, 2, page (424-441)
Statut de publication:Publié, 2010-01
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Bone and Bones -- embryology -- metabolism -- pathology
Cell Differentiation
Cell Proliferation
Cells, Cultured
Endothelial Cells -- cytology
Gene Expression Regulation, Developmental
Humans
Mesoderm -- cytology
Mice
Mice, Transgenic
Morphogenesis
Osteoblasts -- cytology
Phosphatidylinositol 3-Kinases -- metabolism
Stem Cells -- cytology
Stromal Cells -- cytology
Vascular Endothelial Growth Factor A -- genetics -- metabolism
beta Catenin -- genetics -- metabolism
Note générale:Journal Article
Research Support, Non-U.S. Gov't
FLWIN
Langue:Anglais
Identificateurs:urn:issn:0261-4189
info:doi/10.1038/emboj.2009.361
info:pii/emboj2009361
info:pmid/20010698
PMC2824461