par He, Xinrong ;Su, FUHONG ;Velissaris, Dimitrios;Salgado, Diamantino ;de Souza Barros, Dalton;Lorent, Sophie ;Taccone, Fabio ;Vincent, Jean Louis ;De Backer, Daniel
Référence Critical care medicine, 40, 10, page (2833-2840)
Publication Publié, 2012-10
Référence Critical care medicine, 40, 10, page (2833-2840)
Publication Publié, 2012-10
Article révisé par les pairs
Résumé : | Supplementation with tetrahydrobiopterin, a nitric oxide synthase cofactor, may reduce microvascular endothelial dysfunction in severe sepsis. We studied whether tetrahydrobiopterin administration exerts beneficial effects in an ovine septic shock model. |