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Levels of gemcitabine transport and metabolism proteins predict survival times of patients treated with gemcitabine for pancreatic adenocarcinoma.

par Marechal, Raphaël ;Bachet, Jean-Baptiste;Mackey, John R;Dalban, Cécile;Demetter, Pieter ;Graham, Kathryn;Couvelard, Anne;Svrcek, Magali;Bardier-Dupas, Armelle;Hammel, Pascal;Sauvanet, Alain;Louvet, Christophe;Paye, François;Rougier, Philippe;Penna, Christophe;André, Thierry;Dumontet, Charles;Cass, Carol E;Jordheim, Lars Petter;Louvet, Christophe;Closset, Jean ;Salmon, Isabelle ;Devière, Jacques ;Emile, Jean-François;Van Laethem, Jean-Luc
Référence Gastroenterology, 143, 3, page (664-674), e1-6
Publication Publié, 2012-09

Article révisé par les pairs

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Titre:	Levels of gemcitabine transport and metabolism proteins predict survival times of patients treated with gemcitabine for pancreatic adenocarcinoma.
Auteur:	Marechal, Raphaël; Bachet, Jean-Baptiste; Mackey, John R; Dalban, Cécile; Demetter, Pieter; Graham, Kathryn; Couvelard, Anne; Svrcek, Magali; Bardier-Dupas, Armelle; Hammel, Pascal; Sauvanet, Alain; Louvet, Christophe; Paye, François; Rougier, Philippe; Penna, Christophe; André, Thierry; Dumontet, Charles; Cass, Carol E; Jordheim, Lars Petter; Louvet, Christophe; Closset, Jean; Salmon, Isabelle; Devière, Jacques; Emile, Jean-François; Van Laethem, Jean-Luc
Informations sur la publication:	Gastroenterology, 143, 3, page (664-674), e1-6
Statut de publication:	Publié, 2012-09
Sujet CREF:	Sciences humaines
Mots-clés:	Biomarker
	Drug Metabolism
	Nucleoside Transporters
	Pancreatic Cancer
MeSH keywords:	Antimetabolites, Antineoplastic -- metabolism -- therapeutic use
	Biological Transport
	Biotransformation
	Carcinoma, Pancreatic Ductal -- chemistry -- drug therapy -- mortality -- pathology -- surgery
	Chemotherapy, Adjuvant
	Chi-Square Distribution
	Deoxycytidine -- analogs & derivatives -- metabolism -- therapeutic use
	Deoxycytidine Kinase -- analysis
	Equilibrative Nucleoside Transporter 1 -- analysis
	Female
	France
	Humans
	Immunohistochemistry
	Kaplan-Meier Estimate
	Male
	Multivariate Analysis
	Pancreatectomy
	Pancreatic Neoplasms -- chemistry -- drug therapy -- mortality -- pathology -- surgery
	Proportional Hazards Models
	Retrospective Studies
	Risk Assessment
	Risk Factors
	Time Factors
	Tissue Array Analysis -- methods
	Treatment Outcome
	Tumor Suppressor Proteins -- analysis
Note générale:	Journal Article
	Multicenter Study
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0016-5085
	info:doi/10.1053/j.gastro.2012.06.006
	info:pii/S0016-5085(12)00822-0
	info:scp/84865474189
	info:pmid/22705007