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An imbalance in progenitor cell populations reflects tumour progression in breast cancer primary culture models.

par Donatello, Simona ;Hudson, Lance;Cottell, David C;Blanco, Alfonso;Aurrekoetxea, Igor;Shelly, Martin J;Dervan, Peter A;Kell, Malcolm R;Stokes, Maurice;Hill, Arnold D K;Hopkins, Ann M
Référence Journal of experimental & clinical cancer research : CR, 30, page (45)
Publication Publié, 2011-04

Article révisé par les pairs

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Résumé :

Many factors influence breast cancer progression, including the ability of progenitor cells to sustain or increase net tumour cell numbers. Our aim was to define whether alterations in putative progenitor populations could predict clinicopathological factors of prognostic importance for cancer progression.