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Age-dependent changes in rat lacrimal gland anti-oxidant and vesicular related protein expression profiles.

par Batista, Thiago Martins;Tomiyoshi, Lilian Midori;Dias, Ana Carolina;Roma, Leticia P;Módulo, Carolina Maria;Malki, Leonardo Tannus;Filho, Elísio Bueno Machado;Deminice, Rafael;Jordão, Alceu Afonso;Andrade Da Cunha, Daniel ;Rocha, Eduardo Melani
Référence Molecular vision, 18, page (194-202)
Publication Publié, 2012

Article révisé par les pairs

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Résumé :

Anti-oxidation and exocytosis are important for maintaining exocrine tissue homeostasis. During aging, functional and structural alterations occur in the lacrimal gland (LG), including oxidative damage to proteins, lipids, and DNA. The aims of the present study were to determine in the aging LG: a) the effects of aging on LG structure and secretory activity and b) changes in the expression of oxidative stress markers.