par Marhfour, Ihsane ;Moles Lopez, Xavier ;Lefkaditis, Dionysios ;Salmon, Isabelle ;Allagnat, Florent ;Richardson, S J;Morgan, N G;Eizirik, Decio L.
Référence Diabetologia, 55, 9, page (2417-2420)
Publication Publié, 2012
Référence Diabetologia, 55, 9, page (2417-2420)
Publication Publié, 2012
Article révisé par les pairs
Résumé : | Endoplasmic reticulum (ER) stress may play a role in cytokine-mediated beta cell death in type 1 diabetes, but it remains controversial whether ER stress markers are present in islets from type 1 diabetic individuals. Therefore, we evaluated by immunostaining the expression of markers of the three main branches of the ER stress response in islets from 13 individuals with and 15 controls without type 1 diabetes (eight adults and seven children). |