Temporal disorganization of circadian rhythmicity and sleep-wake regulation in mechanically ventilated patients receiving continuous intravenous sedation.

Gehlbach, Brian K; Chapotot, Florian; Leproult, Rachel; Whitmore, Harry; Poston, Jason; Pohlman, Mark; Miller, Annette; Pohlman, Anne S; Nedeltcheva, Arlet; Jacobsen, John H; Hall, Jesse B; Van Cauter, Eve

doi:doi/10.5665/sleep.1998

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Temporal disorganization of circadian rhythmicity and sleep-wake regulation in mechanically ventilated patients receiving continuous intravenous sedation.

par Gehlbach, Brian K ;Chapotot, Florian ;Leproult, Rachel

;Whitmore, Harry ;Poston, Jason ;Pohlman, Mark ;Miller, Annette ;Pohlman, Anne S ;Nedeltcheva, Arlet ;Jacobsen, John H ;Hall, Jesse B ;Van Cauter, Eve

Référence Sleep, 35, 8, page (1105-1114)
Publication Publié, 2012-08

Article révisé par les pairs

Résumé :

Sleep is regulated by circadian and homeostatic processes and is highly organized temporally. Our study was designed to determine whether this organization is preserved in patients receiving mechanical ventilation (MV) and intravenous sedation.

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