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Temporal disorganization of circadian rhythmicity and sleep-wake regulation in mechanically ventilated patients receiving continuous intravenous sedation.

par Gehlbach, Brian K;Chapotot, Florian;Leproult, Rachel ;Whitmore, Harry;Poston, Jason;Pohlman, Mark;Miller, Annette;Pohlman, Anne S;Nedeltcheva, Arlet;Jacobsen, John H;Hall, Jesse B;Van Cauter, Eve
Référence Sleep, 35, 8, page (1105-1114)
Publication Publié, 2012-08

Article révisé par les pairs

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Résumé :

Sleep is regulated by circadian and homeostatic processes and is highly organized temporally. Our study was designed to determine whether this organization is preserved in patients receiving mechanical ventilation (MV) and intravenous sedation.