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Proinflammatory effect of sodium 4-phenylbutyrate in deltaF508-cystic fibrosis transmembrane conductance regulator lung epithelial cells: involvement of extracellular signal-regulated protein kinase 1/2 and c-Jun-NH2-terminal kinase signaling.

par Roque, Telma;Boncoeur, Emilie;Saint-Criq, Vinciane;Bonvin, Elise ;Clement, Annick;Tabary, Olivier;Jacquot, Jacky
Référence The Journal of pharmacology and experimental therapeutics, 326, 3, page (949-956)
Publication Publié, 2008-09

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Titre:	Proinflammatory effect of sodium 4-phenylbutyrate in deltaF508-cystic fibrosis transmembrane conductance regulator lung epithelial cells: involvement of extracellular signal-regulated protein kinase 1/2 and c-Jun-NH2-terminal kinase signaling.
Auteur:	Roque, Telma; Boncoeur, Emilie; Saint-Criq, Vinciane; Bonvin, Elise; Clement, Annick; Tabary, Olivier; Jacquot, Jacky
Informations sur la publication:	The Journal of pharmacology and experimental therapeutics, 326, 3, page (949-956)
Statut de publication:	Publié, 2008-09
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Cell Line
	Cell Survival -- drug effects -- physiology
	Cystic Fibrosis Transmembrane Conductance Regulator -- metabolism
	Dose-Response Relationship, Drug
	Humans
	Inflammation Mediators -- pharmacology -- toxicity
	JNK Mitogen-Activated Protein Kinases -- metabolism
	Lung -- drug effects -- metabolism
	MAP Kinase Signaling System -- drug effects -- physiology
	Mitogen-Activated Protein Kinase 3 -- metabolism
	Phenylbutyrates -- pharmacology -- toxicity
	Respiratory Mucosa -- drug effects -- metabolism
Note générale:	Comparative Study
	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0022-3565
	info:doi/10.1124/jpet.107.135186
	info:pii/jpet.107.135186
	info:pmid/18574003