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Inactivation of adenosine A2A receptor attenuates basal and angiotensin II-induced ROS production by Nox2 in endothelial cells.

par Thakur, Sapna;Du, J.;Hourani, Susanna;Ledent, Catherine ;Li, Jian-Mei
Référence The Journal of biological chemistry, 285, 51, page (40104-40113)
Publication Publié, 2010-12

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Titre:	Inactivation of adenosine A2A receptor attenuates basal and angiotensin II-induced ROS production by Nox2 in endothelial cells.
Auteur:	Thakur, Sapna; Du, J.; Hourani, Susanna; Ledent, Catherine; Li, Jian-Mei
Informations sur la publication:	The Journal of biological chemistry, 285, 51, page (40104-40113)
Statut de publication:	Publié, 2010-12
Sujet CREF:	Sciences biomédicales
MeSH keywords:	Adenosine A2 Receptor Antagonists -- pharmacology
	Angiotensin II -- metabolism -- pharmacology
	Animals
	Cells, Cultured
	Endothelial Cells -- metabolism
	Enzyme Activation -- drug effects -- genetics
	Gene Expression Regulation, Enzymologic -- drug effects -- genetics
	Membrane Glycoproteins -- genetics -- metabolism
	Mice
	Mice, Knockout
	Mitogen-Activated Protein Kinase 3 -- genetics -- metabolism
	NADPH Oxidase -- biosynthesis -- genetics -- metabolism
	Phosphorylation -- drug effects -- genetics
	Proto-Oncogene Proteins c-akt -- genetics -- metabolism
	Pyrimidines -- pharmacology
	Reactive Oxygen Species -- metabolism
	Receptor, Adenosine A2A -- genetics -- metabolism
	Signal Transduction -- drug effects -- physiology
	Triazoles -- pharmacology
	p38 Mitogen-Activated Protein Kinases -- genetics -- metabolism
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0021-9258
	info:doi/10.1074/jbc.M110.184606
	info:pii/M110.184606
	info:scp/78650044035
	info:pmid/20940302
	PMC3000993