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Neutrophil elastase enzymatically antagonizes the in vitro action of G-CSF: implications for the regulation of granulopoiesis.

par El Ouriaghli, Frank ;Fujiwara, Hiroshi;Melenhorst, Jos;Sconocchia, Giuseppe;Hensel, Nancy;Barrett, A John
Référence Blood, 101, 5, page (1752-1758)
Publication Publié, 2003-03

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Titre:	Neutrophil elastase enzymatically antagonizes the in vitro action of G-CSF: implications for the regulation of granulopoiesis.
Auteur:	El Ouriaghli, Frank; Fujiwara, Hiroshi; Melenhorst, Jos; Sconocchia, Giuseppe; Hensel, Nancy; Barrett, A John
Informations sur la publication:	Blood, 101, 5, page (1752-1758)
Statut de publication:	Publié, 2003-03
Sujet CREF:	Cancérologie
MeSH keywords:	Adult
	Antimicrobial Cationic Peptides
	Blood Proteins -- pharmacology
	Carrier Proteins -- pharmacology
	Cathepsin G
	Cathepsins -- pharmacology
	Cells, Cultured -- drug effects
	Feedback, Physiological
	Granulocyte Colony-Stimulating Factor -- antagonists & inhibitors
	Granulocytes -- cytology
	Hematopoiesis -- drug effects -- physiology
	Hematopoietic Stem Cells -- cytology -- drug effects
	Humans
	Leukocyte Elastase -- pharmacology -- physiology
	Myeloblastin
	Phenylmethylsulfonyl Fluoride -- pharmacology
	Protease Inhibitors -- pharmacology
	Receptors, Granulocyte Colony-Stimulating Factor -- drug effects
	Serine Endopeptidases -- pharmacology
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0006-4971
	info:doi/10.1182/blood-2002-06-1734
	info:pii/2002-06-1734
	info:pmid/12393522