Titre:
  • Neutrophil elastase enzymatically antagonizes the in vitro action of G-CSF: implications for the regulation of granulopoiesis.
Auteur:El Ouriaghli, Frank; Fujiwara, Hiroshi; Melenhorst, Jos; Sconocchia, Giuseppe; Hensel, Nancy; Barrett, A John
Informations sur la publication:Blood, 101, 5, page (1752-1758)
Statut de publication:Publié, 2003-03
Sujet CREF:Cancérologie
MeSH keywords:Adult
Antimicrobial Cationic Peptides
Blood Proteins -- pharmacology
Carrier Proteins -- pharmacology
Cathepsin G
Cathepsins -- pharmacology
Cells, Cultured -- drug effects
Feedback, Physiological
Granulocyte Colony-Stimulating Factor -- antagonists & inhibitors
Granulocytes -- cytology
Hematopoiesis -- drug effects -- physiology
Hematopoietic Stem Cells -- cytology -- drug effects
Humans
Leukocyte Elastase -- pharmacology -- physiology
Myeloblastin
Phenylmethylsulfonyl Fluoride -- pharmacology
Protease Inhibitors -- pharmacology
Receptors, Granulocyte Colony-Stimulating Factor -- drug effects
Serine Endopeptidases -- pharmacology
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0006-4971
info:doi/10.1182/blood-2002-06-1734
info:pii/2002-06-1734
info:pmid/12393522