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Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients.

par Bonehill, Aude;Van Nuffel, An M T;Corthals, Jurgen;Tuyaerts, Sandra;Heirman, Carlo;Francois, Violaine ;Colau, Didier;van der Bruggen, P;Neyns, Bart;Thielemans, Kris M.
Référence Clinical cancer research, 15, 10, page (3366-3375)
Publication Publié, 2009-05

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Titre:	Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients.
Auteur:	Bonehill, Aude; Van Nuffel, An M T; Corthals, Jurgen; Tuyaerts, Sandra; Heirman, Carlo; Francois, Violaine; Colau, Didier; van der Bruggen, P; Neyns, Bart; Thielemans, Kris M.
Informations sur la publication:	Clinical cancer research, 15, 10, page (3366-3375)
Statut de publication:	Publié, 2009-05
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Antigens, CD137 -- metabolism
	Antigens, CD70 -- genetics -- immunology
	Antigens, Neoplasm -- genetics -- immunology
	Cancer Vaccines -- genetics -- immunology
	Cytokines -- metabolism
	Dendritic Cells -- cytology -- immunology -- metabolism
	Electroporation -- methods
	Female
	Flow Cytometry
	Humans
	Lysosomal-Associated Membrane Protein 1 -- metabolism
	MART-1 Antigen
	Male
	Melanoma -- immunology -- pathology
	Membrane Glycoproteins -- genetics -- immunology
	Monophenol Monooxygenase -- genetics -- immunology
	Neoplasm Proteins -- genetics -- immunology
	Neoplasm Staging
	RNA, Messenger -- genetics
	Toll-Like Receptor 4 -- genetics -- immunology
	Vaccination -- methods
	gp100 Melanoma Antigen
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:1078-0432
	info:doi/10.1158/1078-0432.CCR-08-2982
	info:pii/1078-0432.CCR-08-2982
	info:pmid/19417017