Parasitic loads in tissues of mice infected with Trypanosoma cruzi and treated with AmBisome.

Cencig, Sabrina; Coltel, Nicolas; Truyens, Carine; Carlier, Yves

doi:doi/10.1371/journal.pntd.0001216

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Parasitic loads in tissues of mice infected with Trypanosoma cruzi and treated with AmBisome.

par Cencig, Sabrina

;Coltel, Nicolas

;Truyens, Carine

;Carlier, Yves

Référence P L o S Neglected Tropical Diseases, 5, 6, page (e1216)
Publication Publié, 2011-06

Article révisé par les pairs

Résumé :

Chagas disease is one of the most important public health problems and a leading cause of cardiac failure in Latin America. The currently available drugs to treat T. cruzi infection (benznidazole and nifurtimox) are effective in humans when administered during months. AmBisome (liposomal amphotericin B), already shown efficient after administration for some days in human and experimental infection with Leishmania, has been scarcely studied in T. cruzi infection.

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