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Implication of tumor microenvironment in the resistance to chemotherapy in breast cancer patients.

par Andre, Fabrice;Berrada, Narjiss;Desmedt, Christine
Référence Current opinion in oncology, 22, 6, page (547-551)
Publication Publié, 2010-11

Article révisé par les pairs

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Résumé :

Chemotherapy is a cornerstone treatment in patients with early breast cancer. Although some cancer cell-related predictors are emerging, the indications of chemotherapy and the choice of chemotherapy regimen are not individualized enough, emphasizing the need for new predictors. This review will summarize recent advances concerning the implication of tumor microenvironment in the response to chemotherapy.