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Glycogen synthase kinase 3 involvement in the excessive proinflammatory response to LPS in patients with decompensated cirrhosis.

par Coant, Nicolas;Simon-Rudler, Marika;Gustot, Thierry ;Fasseu, Magali;Gandoura, Sonia;Ragot, Kévin;Abdel-Razek, Waël;Thabut, Dominique;Lettéron, Philippe;Ogier-Denis, Eric;Ouziel, Romy ;Devière, Jacques ;Lizard, Gérard;Tellier, Zéra;Lebrec, Didier;Moreau, R.
Référence Journal of hepatology, 55, 4, page (784-793)
Publication Publié, 2011-10

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Titre:	Glycogen synthase kinase 3 involvement in the excessive proinflammatory response to LPS in patients with decompensated cirrhosis.
Auteur:	Coant, Nicolas; Simon-Rudler, Marika; Gustot, Thierry; Fasseu, Magali; Gandoura, Sonia; Ragot, Kévin; Abdel-Razek, Waël; Thabut, Dominique; Lettéron, Philippe; Ogier-Denis, Eric; Ouziel, Romy; Devière, Jacques; Lizard, Gérard; Tellier, Zéra; Lebrec, Didier; Moreau, R.
Informations sur la publication:	Journal of hepatology, 55, 4, page (784-793)
Statut de publication:	Publié, 2011-10
Sujet CREF:	Soins intensifs réanimation
	Immunologie
	Gastro-entérologie
Mots-clés:	AKT
	Alcohol
	Cirrhosis
	Glycogen synthase kinase 3
	Innate immunity
	Lipopolysaccharides
MeSH keywords:	Adjuvants, Immunologic -- pharmacology
	Adult
	Aged
	Cells, Cultured
	Female
	Gene Expression Regulation, Enzymologic -- immunology
	Glycogen Synthase Kinase 3 -- antagonists & inhibitors -- genetics -- immunology -- metabolism
	Hepatitis -- immunology -- metabolism
	Humans
	Indoles -- pharmacology
	Interleukin-10 -- immunology -- metabolism
	Interleukin-12 -- immunology -- metabolism
	Lipopolysaccharides -- pharmacology
	Lithium Chloride -- pharmacology
	Liver Cirrhosis -- immunology -- metabolism
	Male
	Maleimides -- pharmacology
	Middle Aged
	Monocytes -- immunology -- metabolism
	Proto-Oncogene Proteins c-akt -- genetics
	Severity of Illness Index
	Signal Transduction -- immunology
	Toll-Like Receptor 4 -- immunology -- metabolism
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0168-8278
	info:doi/10.1016/j.jhep.2010.12.039
	info:pii/S0168-8278(11)00162-0
	info:scp/80052950765
	info:pmid/21334395