par Compain, Guillaume;Jouvin, Kevin;Martin-Mingot, Agnès;Evano, Gwilherm ;Marrot, Jérôme;Thibaudeau, Sébastien
Référence Chemical communications
Publication Publié, 2012
Référence Chemical communications
Publication Publié, 2012
Article révisé par les pairs
Résumé : | alpha-Fluoroenamides, potent rigid fluorinated bioisosters of ureas,have been synthesized by a highly regio- and stereo-selective hydrofluorination of ynamides in anhydrous HF. This reaction provides the first general entry to alpha-fluoroenamides and can easily be applied to a wide range of substrates. |