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Global microRNA expression profiling identifies MiR-210 associated with tumor proliferation, invasion and poor clinical outcome in breast cancer.

par Rothé, Françoise ;Ignatiadis, Michail ;Chaboteaux, Carole ;Haibe-Kains, Benjamin ;Kheddoumi, Naima ;Majjaj, Samira ;Badran, Bassam ;Fayyad Kazan, Hussein ;Desmedt, Christine ;Harris, Adrian L;Piccart-Gebhart, Martine ;Sotiriou, Christos
Référence PloS one, 6, 6, page (e20980)
Publication Publié, 2011

Article révisé par les pairs

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Résumé :

Aberrant microRNA (miRNA) expression is associated with cancer and has potential diagnostic and prognostic value in various malignancies. In this study, we investigated miRNA profiling as a complementary tool to improve our understanding of breast cancer (BC) biology and to assess whether miRNA expression could predict clinical outcome of BC patients.