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KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab.

par De Roock, Wendy;Piessevaux, Hubert;De Schutter, Jef;Janssens, Muriel ;De Hertogh, Gert;Personeni, Nicola;Biesmans, Bart;Van Laethem, Jean-Luc ;Peeters, Michel ;Humblet, Yves;Van Cutsem, Eric;Tejpar, Sabine
Référence Annals of oncology, 19, 3, page (508-515)
Publication Publié, 2008-03

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Titre:	KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab.
Auteur:	De Roock, Wendy; Piessevaux, Hubert; De Schutter, Jef; Janssens, Muriel; De Hertogh, Gert; Personeni, Nicola; Biesmans, Bart; Van Laethem, Jean-Luc; Peeters, Michel; Humblet, Yves; Van Cutsem, Eric; Tejpar, Sabine
Informations sur la publication:	Annals of oncology, 19, 3, page (508-515)
Statut de publication:	Publié, 2008-03
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Cetuximab
	Colorectal cancer
	EGFR
	KRAS
	Survival
MeSH keywords:	Antibodies, Monoclonal -- therapeutic use
	Antineoplastic Agents -- therapeutic use
	Antineoplastic Combined Chemotherapy Protocols
	Camptothecin -- administration & dosage -- analogs & derivatives
	Colorectal Neoplasms -- drug therapy -- genetics -- mortality -- radiography
	Disease-Free Survival
	Female
	Humans
	Logistic Models
	Male
	Middle Aged
	Mutation
	Proportional Hazards Models
	Proto-Oncogene Proteins -- analysis
	Retrospective Studies
	Sensitivity and Specificity
	Survival Rate
	Tomography, X-Ray Computed
	ras Proteins -- analysis
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0923-7534
	info:doi/10.1093/annonc/mdm496
	info:pii/mdm496
	info:scp/40149088765
	info:pmid/17998284