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Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab.

par Jacobs, Bart;De Roock, Wendy;Piessevaux, Hubert;Van Oirbeek, Robin;Biesmans, Bart;De Schutter, Jef;Fieuws, Steffen;Vandesompele, Jo;Peeters, Marc;Van Laethem, Jean-Luc ;Humblet, Yves;Pénault-Llorca, Frederique;De Hertogh, Gert;Laurent, Pierre ;Van Cutsem, Eric;Tejpar, Sabine
Référence Journal of clinical oncology, 27, 30, page (5068-5074)
Publication Publié, 2009-10

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Titre:	Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab.
Auteur:	Jacobs, Bart; De Roock, Wendy; Piessevaux, Hubert; Van Oirbeek, Robin; Biesmans, Bart; De Schutter, Jef; Fieuws, Steffen; Vandesompele, Jo; Peeters, Marc; Van Laethem, Jean-Luc; Humblet, Yves; Pénault-Llorca, Frederique; De Hertogh, Gert; Laurent, Pierre; Van Cutsem, Eric; Tejpar, Sabine
Informations sur la publication:	Journal of clinical oncology, 27, 30, page (5068-5074)
Statut de publication:	Publié, 2009-10
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Antibodies, Monoclonal -- therapeutic use
	Antineoplastic Agents -- therapeutic use
	Camptothecin -- analogs & derivatives -- therapeutic use
	Cohort Studies
	Colorectal Neoplasms -- drug therapy -- genetics -- mortality -- secondary
	Epidermal Growth Factor -- genetics
	Gene Expression
	Glycoproteins -- biosynthesis -- genetics
	Humans
	Intercellular Signaling Peptides and Proteins -- biosynthesis -- genetics
	Ligands
	Prognosis
	Proto-Oncogene Proteins -- genetics
	RNA, Messenger -- genetics
	Receptor, Epidermal Growth Factor -- antagonists & inhibitors -- genetics
	Survival Analysis
	ras Proteins -- genetics
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0732-183X
	info:doi/10.1200/JCO.2008.21.3744
	info:pii/JCO.2008.21.3744
	info:pmid/19738126