Titre:
  • Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors.
Auteur:Flipo, Marion; Desroses, Matthieu; Lecat-Guillet, Nathalie; Villemagne, Baptiste; Blondiaux, Nicolas; Leroux, Florence; Piveteau, Catherine; Mathys, Vanessa; Flament, Marie-Pierre; Siepmann, Juergen; Villeret, Vincent; Wohlkonig, Alexandre; Wintjens, René; Soror, Sameh H; Christophe, Thierry; Jeon, Hee Kyoung; Locht, Camille; Brodin, Priscille; Déprez, Benoit; Baulard, Alain; Willand, Nicolas
Informations sur la publication:Journal of medicinal chemistry, 55, 1, page (68-83)
Statut de publication:Publié, 2012-01
Sujet CREF:Biologie
Mots-clés:Biologie structurale
Note générale:Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0022-2623
info:doi/10.1021/jm200825u
info:scp/84855832075
info:pmid/22098589