Titre:
  • Molecular genetics of para-aminosalicylic acid resistance in clinical isolates and spontaneous mutants of Mycobacterium tuberculosis.
Auteur:Mathys, Vanessa; Wintjens, René; Lefèvre, Philippe; Bertout, Julie; Singhal, Amit; Kiass, Mehdi; Kurepina, Natalia; Wang, Xiao-Jing; Mathema, Barun; Baulard, Alain; Kreiswirth, Barry N; Bifani, Juan Pablo
Informations sur la publication:Antimicrobial agents and chemotherapy, 53, 5, page (2100-2109)
Statut de publication:Publié, 2009-05
Sujet CREF:Biologie
Mots-clés:Biologie structurale
MeSH keywords:Aminosalicylic Acid -- pharmacology
Antitubercular Agents -- pharmacology
Bacterial Proteins -- genetics
Drug Resistance, Bacterial -- genetics
Folic Acid -- biosynthesis
Humans
Microbial Sensitivity Tests
Mutation
Mycobacterium tuberculosis -- drug effects -- enzymology -- genetics
Structure-Activity Relationship
Thymidylate Synthase -- genetics
Thymine -- biosynthesis
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0066-4804
info:doi/10.1128/AAC.01197-08
info:pii/AAC.01197-08
info:scp/66149143506
info:pmid/19237648
PMC2681553