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Synthesis of lipophilic dimeric C-7/C-7-linked ciprofloxacin and C-6/C-6-linked levofloxacin derivatives. Versatile in vitro biological evaluations of monomeric and dimeric fluoroquinolone derivatives as potential antitumor, antibacterial or antimycobacterial agents.

par Azéma, Joëlle;Guidetti, Brigitte;Korolyov, Alexander;Kiss, Robert ;Roques, Christine;Constant, Patricia;Daffé, Mamadou;Malet-Martino, Myriam
Référence European journal of medicinal chemistry, 46, 12, page (6025-6038)
Publication Publié, 2011-12

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Titre:	Synthesis of lipophilic dimeric C-7/C-7-linked ciprofloxacin and C-6/C-6-linked levofloxacin derivatives. Versatile in vitro biological evaluations of monomeric and dimeric fluoroquinolone derivatives as potential antitumor, antibacterial or antimycobacterial agents.
Auteur:	Azéma, Joëlle; Guidetti, Brigitte; Korolyov, Alexander; Kiss, Robert; Roques, Christine; Constant, Patricia; Daffé, Mamadou; Malet-Martino, Myriam
Informations sur la publication:	European journal of medicinal chemistry, 46, 12, page (6025-6038)
Statut de publication:	Publié, 2011-12
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Fluoroquinolones
	In vitro antibacterial activity
	In vitro antimycobacterial activity
	In vitro antitumor activity
	Lipophilic ciprofloxacin and levofloxacin dimeric derivatives
Note générale:	Journal Article
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0223-5234
	info:doi/10.1016/j.ejmech.2011.10.014
	info:pii/S0223-5234(11)00731-8
	info:scp/80955137592
	info:pmid/22036229