par Cimmino, Alessio;Evidente, Antonio;Mathieu, V;Andolfi, Anna;Lefranc, Florence 
;Kornienko, Alexander;Kiss, Robert
Référence Natural product reports
Publication Publié, 2012-02
;Kornienko, Alexander;Kiss, Robert Référence Natural product reports
Publication Publié, 2012-02
Article révisé par les pairs
| Résumé : | Covering: 2000 to 2011Phenazines are a large group of natural and synthesised nitrogen-containing heterocycles, including more than 100 different compounds of natural origin and over 6000 synthetic compounds. Many of these compounds have been investigated as potential anti-cancer agents. Despite a large number of research publications, no recent attempt to summarise and critically evaluate the experimental findings relating to the anti-cancer activity of this class of compounds has been made. The present review fills this gap in the literature and discusses both natural and synthetic phenazines with a critical focus on in vitro, in vivo and available clinical anti-cancer activities of these compounds. |
