• Citer

HPLC quantification of zolpidem and prothipendyl in a voluntary intoxication.

par Debailleul, G;Khalil, F A;Lheureux, Philippe
Référence Journal of analytical toxicology, 15, 1, page (35-37)
Publication Publié, 1991

Article révisé par les pairs

• Détails
• Contenu

Résumé :

Zolpidem, a recently developed sleep inducer, and prothipendyl, a neuroleptic azaphenothiazine, were involved in a voluntary intoxication along with ethanol. After administration of flumazenil, a specific benzodiazepines antagonist, respiratory depression was corrected. HPLC with UV detection methods after selective extraction were developed to measure simultaneously prothipendyl and zolpidem without flumazenil interaction. These methods could be applied in drug monitoring and in emergency toxicology.