par Biver, Sophie ;Scohy, Sophie ;Szpirer, Josiane ;Szpirer, Claude ;André, Bruno ;Marini, Anna Maria
Référence Transfusion clinique et biologique, 13, 1-2 SPEC. ISS., page (167-168)
Publication Publié, 2006-03
Référence Transfusion clinique et biologique, 13, 1-2 SPEC. ISS., page (167-168)
Publication Publié, 2006-03
Article révisé par les pairs
Résumé : | Ammonium excretion into urine is a major process essential to the regulation of acid-base homeostasis. We have shown that Rh-type proteins, including renal RhCG, belong to the Mep/Amt family of ammonium transporters and promote bi-directional ammonium transport upon heterologous expression in yeast. To study the physiological role of RhCG and to test a potential function in ammonium excretion, we have generated mice bearing an invalidation of the corresponding gene. © 2006 Elsevier SAS. All rights reserved. |