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Practical use of GenoType® HelicoDR, a molecular test for Helicobacter pylori detection and susceptibility testing.

par Miendje Deyi, Yvette Véro ;Burette, Alain;Bentatou, Zahra;Maaroufi, Younes ;Bontems, Patrick ;Lepage, Philippe ;Reynders, Marijke
Référence Diagnostic microbiology and infectious disease, 70, 4, page (557-560)
Publication Publié, 2011-08

Article révisé par les pairs

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Résumé :

Compared to culture-based method, the sensitivity, specificity, positive, and negative predictive values of the GenoType(®) HelicoDR for detecting Helicobacter pylori resistance were, respectively, 100, 86.2, 89.7%, and 100% to clarithromycin as well as 82.6, 95.1, 90.5%, and 90.7% to fluoroquinolones. This molecular assay detected a mixture of genotypes and could successfully analyze biopsies without transport/storage limitations.