par Knoop, Christiane ;Vervier, Ingrid;Thiry, Philippe ;De Backer, Marc;Kovarik, John M.;Rousseau, Annick;Marquet, Pierre;Estenne, Marc
Référence Transplantation, 76, 4, page (683-688)
Publication Publié, 2003-08
Référence Transplantation, 76, 4, page (683-688)
Publication Publié, 2003-08
Article révisé par les pairs
Résumé : | In cystic fibrosis (CF), absorption of cyclosporine A (CsA) through the gastrointestinal tract is often impaired because of fat malabsorption. The aim of this study was to compare the steady-state pharmacokinetics of CsA and the inter- and intrasubject variability of CsA exposure in stable lung transplant recipients with and without CF and to determine the best single-time predictors of the area under the curve (AUC). |