Titre :
  • Nucleotide-induced conformational changes in the human multidrug resistance protein MRP1 are related to the capacity of chemotherapeutic drugs to accumulate or not in resistant cells.
Auteur : Manciu, Liliane ; Chang, XB. ; Riordan, John R ; Buyse, Frédéric ; Ruysschaert, Jean Marie
Informations sur la publication : FEBS letters, 493, 1, (page 31-35)
Statut de publication : Publié, 2001-03
Sujet CREF : Chimie
Mots-clés MeSH : ATP-Binding Cassette Transporters -- chemistry
ATP-Binding Cassette Transporters -- metabolism
Acrylamide -- pharmacology
Adenosine Triphosphatases -- metabolism
Antibiotics, Antineoplastic -- pharmacology
Antineoplastic Agents -- pharmacology
Binding Sites
Biological Transport
Catalytic Domain
Cell Line
Cell Membrane -- metabolism
Daunorubicin -- pharmacology
Dose-Response Relationship, Drug
Doxorubicin -- pharmacology
Drug Resistance, Neoplasm
Flow Cytometry
Humans
Kinetics
Models, Chemical
Multidrug Resistance-Associated Proteins
Protein Binding
Protein Conformation -- drug effects
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0014-5793 
info:pii/S0014579301022700
info:pmid/11278000