Titre :
  • Arylcyanoguanidines as activators of Kir6.2/SUR1K ATP channels and inhibitors of insulin release.
Auteur : Tagmose, Tina M ; Schou, Søren C ; Mogensen, John P ; Nielsen, Flemming E ; Arkhammar, Per O G ; Wahl, Philip ; Hansen, Birgit S ; Worsaae, Anne ; Boonen, Harrie C M ; Antoine, Marie-Hélène ; Lebrun, Philippe ; Hansen, John Bondo
Informations sur la publication : Journal of medicinal chemistry, 47, 12, (page 3202-3211)
Statut de publication : Publié, 2004-06
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : ATP-Binding Cassette Transporters -- agonists
Animals
Aorta -- drug effects
Aorta -- physiology
Cell Line
Female
Glucose -- metabolism
Guanidines -- chemical synthesis
Guanidines -- chemistry
Guanidines -- pharmacology
Humans
Insulin Antagonists -- chemical synthesis
Insulin Antagonists -- chemistry
Insulin Antagonists -- pharmacology
Islets of Langerhans -- drug effects
Islets of Langerhans -- physiology
Male
Mitochondria -- drug effects
Mitochondria -- physiology
Muscle Relaxation -- drug effects
Muscle, Smooth, Vascular -- drug effects
Muscle, Smooth, Vascular -- physiology
Nitriles -- chemical synthesis
Nitriles -- chemistry
Nitriles -- pharmacology
Oocytes -- drug effects
Oocytes -- physiology
Oxidation-Reduction
Patch-Clamp Techniques
Potassium Channels -- agonists
Potassium Channels, Inwardly Rectifying -- drug effects
Rats
Rats, Sprague-Dawley
Receptors, Drug -- agonists
Structure-Activity Relationship
Xenopus laevis
Note : In Vitro
Journal Article
Langue :
  • Anglais
Identificateurs : urn:issn:0022-2623 
info:doi/10.1021/jm031018y
info:pmid/15163199