par Vandenberghe, E;Martiat, Philippe ;Baens, M;Stul, Michel;Ferrant, Augustin;Cuneo, A;Cassiman, J.-J.;Mecucci, C;Van den Berghe, Herman
Référence Leukemia, 5, 8, page (683-686)
Publication Publié, 1991-08
Référence Leukemia, 5, 8, page (683-686)
Publication Publié, 1991-08
Article révisé par les pairs
Résumé : | A patient is described with de novo acute non-lymphocytic leukemia of megakaryoblastic lineage with tri-lineage myelodysplasia. This patient was studied cytogenetically and using molecular genetic techniques throughout her clinical course. She had an N-ras mutation at diagnosis which persisted despite a bone marrow transplant, and acquired a Philadelphia chromosome associated with a P190 BCR-ABL transcript at clinical relapse 3 months post-transplantation. |