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DNA-binding fingers encoded by a trypanosome retroposon.

par Pays, Etienne ;Murphy, N B
Référence Journal of Molecular Biology, 197, 1, page (147-148)
Publication Publié, 1987-09

Article révisé par les pairs

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Résumé :

A Trypanosoma brucei repeated DNA element (TRS-1, for trypanosome repeated sequence), which seems transposable, may encode a 1651 amino acid polypeptide showing homology with reverse transcriptase. This polypeptide would also carry a DNA-binding domain, as suggested by the presence of five DNA-binding "fingers" homologous to those of the transcription factor TFIIIA of Xenopus laevis and retroviral DNA-binding proteins.