Titre :
  • A chromosomal SIR2 homologue with both histone NAD-dependent ADP-ribosyltransferase and deacetylase activities is involved in DNA repair in Trypanosoma brucei.
Auteur : García-Salcedo, José A ; Gijón, Purificación ; Nolan, Derek ; Tebabi, Patricia ; Pays, Etienne
Informations sur la publication : EMBO journal, 22, 21, (page 5851-5862)
Statut de publication : Publié, 2003-11
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : DNA damage
Histone deacetylase
Histone ribosyltransferase
SIR2 homologue
Trypanosoma
Mots-clés MeSH : Alkylating Agents -- toxicity
Animals
DNA Damage
DNA Repair -- genetics
DNA Repair -- physiology
Genes, Protozoan
Histone Deacetylases -- metabolism
Histones -- metabolism
Nuclear Proteins -- metabolism
Protozoan Proteins -- metabolism
Sirtuins -- metabolism
Substrate Specificity
Trypanosoma brucei brucei -- drug effects
Trypanosoma brucei brucei -- genetics
Trypanosoma brucei brucei -- metabolism
Note : In Vitro
Journal Article
Research Support, Non-U.S. Gov't
FLWIN
Langue :
  • Anglais
Identificateurs : urn:issn:0261-4189 
info:doi/10.1093/emboj/cdg553
info:pmid/14592982
info:pmcid/PMC275410