par Del Marmol, Véronique 
;Ito, S;Jackson, I;Vachtenheim, J;Berr, Pascale ;Ghanem, Ghanem Elias ;Morandini, R;Wakamatsu, K;Huez, Georges
Référence FEBS letters, 327, 3, page (307-310)
Publication Publié, 1993-08
;Ito, S;Jackson, I;Vachtenheim, J;Berr, Pascale ;Ghanem, Ghanem Elias ;Morandini, R;Wakamatsu, K;Huez, Georges Référence FEBS letters, 327, 3, page (307-310)
Publication Publié, 1993-08
Article révisé par les pairs
| Résumé : | We have investigated the relationship in human cultured normal and malignant melanocytes between the accumulation of mRNAs encoding tyrosinase and tyrosinase-related protein-1 (TRP-1), the activity of tyrosinase and the presence of melanin. Tyrosinase mRNA correlates with tyrosinase activity and with the presence of pheomelanin, eumelanin or both melanin types. In contrast TRP-1 mRNA is only detectable in cells containing eumelanin, which suggests a role for TRP-1 in the eumelanin synthesis pathway. |
