Titre :
  • Inhibition of Th1 immune response by glucocorticoids: dexamethasone selectively inhibits IL-12-induced Stat4 phosphorylation in T lymphocytes.
Auteur : Franchimont, Denis ; Galon, J ; Gadina, M ; Visconti, R ; Zhou, Y ; Aringer, M ; Frucht, D M ; Chrousos, G P ; O'Shea, J J
Informations sur la publication : The Journal of immunology, 164, 4, (page 1768-1774)
Statut de publication : Publié, 2000-02
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : 3T3 Cells
Animals
DNA-Binding Proteins -- antagonists & inhibitors
DNA-Binding Proteins -- biosynthesis
DNA-Binding Proteins -- genetics
DNA-Binding Proteins -- metabolism
Dexamethasone -- pharmacology
Humans
Immunosuppressive Agents -- pharmacology
Interferon Regulatory Factor-1
Interferon-gamma -- antagonists & inhibitors
Interferon-gamma -- biosynthesis
Interleukin-12 -- antagonists & inhibitors
Interleukin-12 -- metabolism
Interleukin-12 -- physiology
Janus Kinase 2
Mice
Phosphoproteins -- antagonists & inhibitors
Phosphoproteins -- biosynthesis
Phosphoproteins -- genetics
Phosphorylation -- drug effects
Promoter Regions, Genetic -- drug effects
Promoter Regions, Genetic -- immunology
Protein-Tyrosine Kinases -- antagonists & inhibitors
Protein-Tyrosine Kinases -- metabolism
Proteins -- antagonists & inhibitors
Proteins -- metabolism
Proto-Oncogene Proteins
Receptors, Interleukin -- metabolism
Receptors, Interleukin-12
STAT4 Transcription Factor
Signal Transduction -- drug effects
Signal Transduction -- immunology
T-Lymphocytes -- drug effects
T-Lymphocytes -- metabolism
TYK2 Kinase
Th1 Cells -- drug effects
Th1 Cells -- immunology
Trans-Activators -- antagonists & inhibitors
Trans-Activators -- metabolism
Transfection
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0022-1767 
info:pii/ji_v164n4p1768
info:pmid/10657623