Titre :
  • Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity.
Auteur : Costagliola, Sabine ; Bonomi, M ; Morgenthaler, N G ; Van Durme, Joost ; Panneels, Valérie ; Refetoff, Samuel ; Vassart, Gilbert
Informations sur la publication : Molecular endocrinology, 18, 12, (page 3020-3034)
Statut de publication : Publié, 2004-12
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Amino Acid Sequence
Animals
Antibodies, Monoclonal -- immunology
Antibodies, Monoclonal -- pharmacology
Autoantibodies -- immunology
Autoantibodies -- pharmacology
Binding Sites, Antibody -- genetics
Binding Sites, Antibody -- immunology
Cyclic AMP -- metabolism
Disease Models, Animal
Epitope Mapping
Female
Graves Disease -- immunology
Humans
Hybridomas
Hyperthyroidism -- chemically induced
Hyperthyroidism -- immunology
Hyperthyroidism -- pathology
Immunoglobulin Fab Fragments -- immunology
Immunoglobulins, Thyroid-Stimulating
Mice
Molecular Sequence Data
Receptors, Thyrotropin -- agonists
Receptors, Thyrotropin -- chemistry
Receptors, Thyrotropin -- immunology
Thyroid Gland -- drug effects
Thyroid Gland -- pathology
Thyroiditis, Autoimmune -- immunology
Thyrotropin -- blood
Thyrotropin -- physiology
Thyroxine -- blood
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0888-8809 
info:doi/10.1210/me.2004-0231
info:pii/me.2004-0231
info:pmid/15319453