Titre :
  • RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia.
Auteur : Simonin, Frédéric ; Schmitt, M. ; Laulin, Jean-Paul ; Laboureyras, Emilie ; Jhamandas, Jack H ; MacTavish, David ; Matifas, Audrey ; Mollereau, Catherine ; Laurent, Patrick ; Parmentier, Marc ; Kieffer, Brigitte L ; Bourguignon, Jean-Jacques ; Simonnet, Guy
Informations sur la publication : Proceedings of the National Academy of Sciences of the United States of America, 103, 2, (page 466-471)
Statut de publication : Publié, 2006-01
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Analgesia
Antiopioid
Cardiac function
RFamide
Mots-clés MeSH : Adamantane -- analogs & derivatives
Adamantane -- chemistry
Adamantane -- pharmacology
Amides -- chemistry
Analgesics, Opioid -- antagonists & inhibitors
Analgesics, Opioid -- pharmacology
Animals
Blood Pressure -- drug effects
COS Cells
Cercopithecus aethiops
Dipeptides -- chemistry
Dipeptides -- pharmacology
Drug Tolerance
Heart Rate -- drug effects
Heroin -- antagonists & inhibitors
Heroin -- pharmacology
Humans
Hyperalgesia -- chemically induced
Hyperalgesia -- metabolism
Hyperalgesia -- physiopathology
Ligands
Molecular Structure
Rats
Receptors, Neuropeptide -- antagonists & inhibitors
Receptors, Neuropeptide -- metabolism
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0027-8424 
info:doi/10.1073/pnas.0502090103
info:pii/0502090103
info:pmid/16407169
info:pmcid/PMC1326150