Titre :
  • Benzene polyphosphates as tools for cell signalling: inhibition of inositol 1,4,5-trisphosphate 5-phosphatase and interaction with the PH domain of protein kinase Balpha.
Auteur : Mills, Stephen J ; Vandeput, Fabrice ; Trusselle, Melanie N ; Safrany, Stephen T ; Erneux, Christophe ; Potter, Barry V L
Informations sur la publication : ChemBioChem, 9, 11, (page 1757-1766)
Statut de publication : Publié, 2008-07
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Benzene polyphosphates
Molecular modeling
Phosphatases
Pi interactions
PKBα PH domain
Mots-clés MeSH : Benzene -- chemistry
Binding Sites
Fluorescence Resonance Energy Transfer
Ligands
Models, Molecular
Phosphoric Monoester Hydrolases -- antagonists & inhibitors
Phosphoric Monoester Hydrolases -- chemistry
Phosphoric Monoester Hydrolases -- metabolism
Polyphosphates -- chemical synthesis
Polyphosphates -- chemistry
Polyphosphates -- pharmacology
Protein Structure, Tertiary
Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
Proto-Oncogene Proteins c-akt -- chemistry
Proto-Oncogene Proteins c-akt -- metabolism
Signal Transduction -- drug effects
Stereoisomerism
Structure-Activity Relationship
Note : Journal Article
Research Support, Non-U.S. Gov't
FLWNA
Langue :
  • Anglais
Identificateurs : urn:issn:1439-4227 
info:doi/10.1002/cbic.200800104
info:pmid/18574825
info:pmcid/PMC2666327