Titre :
  • The Amaryllidaceae isocarbostyril narciclasine induces apoptosis by activation of the death receptor and/or mitochondrial pathways in cancer cells but not in normal fibroblasts.
Auteur : Dumont, Patrick P. ; Ingrassia, Laurent ; Rouzeau, Sébastien ; Ribaucour, Fabrice ; Thomas, Stéphanie ; Roland, Isabelle ; Darro, Francis ; Lefranc, Florence ; Kiss, Robert
Informations sur la publication : Neoplasia (New York, N.Y.), 9, 9, (page 766-776)
Statut de publication : Publié, 2007-09
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Amaryllidaceae Alkaloids -- isolation & purification
Amaryllidaceae Alkaloids -- pharmacology
Antigens, CD95 -- drug effects
Antigens, CD95 -- physiology
Antineoplastic Agents, Phytogenic -- isolation & purification
Antineoplastic Agents, Phytogenic -- pharmacology
Apoptosis -- drug effects
Apoptosis -- physiology
BH3 Interacting Domain Death Agonist Protein -- physiology
Breast Neoplasms -- metabolism
Breast Neoplasms -- pathology
Carcinoma -- metabolism
Carcinoma -- pathology
Caspases -- physiology
Cytochromes c -- analysis
DNA Fragmentation
Drug Resistance, Neoplasm
Enzyme Activation -- drug effects
Female
Fibroblasts -- drug effects
Humans
Male
Mitochondria -- enzymology
Mitochondria -- physiology
Narcissus -- chemistry
Neoplasm Proteins -- drug effects
Neoplasm Proteins -- physiology
Phenanthridines -- isolation & purification
Phenanthridines -- pharmacology
Prostatic Neoplasms -- metabolism
Prostatic Neoplasms -- pathology
Receptors, Tumor Necrosis Factor -- physiology
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:1476-5586 
info:pmid/17898872
info:pmcid/PMC1993861