Titre :
  • New structural insights into the apelin receptor: identification of key residues for apelin binding.
Auteur : Gerbier, Romain ; Leroux, Vincent ; Couvineau, Pierre P ; Alvear-Perez, Rodrigo R ; Maigret, Bernard ; Llorens-Cortes, Catherine C ; Iturrioz, Xavier X
Informations sur la publication : The FASEB journal, 29, 1, (page 314-322)
Statut de publication : Publié, 2015-01
Sujet CREF : Sciences bio-médicales et agricoles
Sciences exactes et naturelles
Mots-clés : APJ
G protein–coupled receptor
homology models
molecular modeling
site-directed mutagenesis
Mots-clés MeSH : Amino Acid Sequence
Amino Acid Substitution
Animals
Binding Sites -- genetics
Conserved Sequence
Cyclic AMP -- biosynthesis
Humans
Intercellular Signaling Peptides and Proteins -- metabolism
Models, Molecular
Molecular Sequence Data
Multiprotein Complexes -- chemistry
Mutagenesis, Site-Directed
Protein Conformation
Rats
Receptors, G-Protein-Coupled -- chemistry -- genetics -- metabolism
Recombinant Fusion Proteins -- chemistry -- genetics -- metabolism
Sequence Homology, Amino Acid
Structural Homology, Protein
Langue :
  • Anglais
Identificateurs : urn:issn:0892-6638 
info:doi/10.1096/fj.14-256339
info:pii/fj.14-256339
info:pmid/25359495