par Achten, Georges 
;De Maubeuge, Josiane
Référence Archives Francaises des Maladies de l'Appareil Digestif, 64, 7, page (561-572)
Publication Publié, 1975
;De Maubeuge, JosianeRéférence Archives Francaises des Maladies de l'Appareil Digestif, 64, 7, page (561-572)
Publication Publié, 1975
Article révisé par les pairs
| Résumé : | Pruritogenic factors stimulate, by means of chemical mediators (histamine, proteinases, kinins, prostaglandins) some receptors of low threshold composed of an aggregate of thin unmyelinated fibers and of nerve endings in the subepidermal area. Itching is induced by weak stimuli acting on those 'itch points'. Increase in the intensity of the stimulus leads to pain. Sensory messages are carried along afferent fibers to the spinal cord and finally to the cerebral cortex leading to the perception of this sensation and to scratching. Anal pruritus is one of the most frequently encountered: local conditions (cutaneous folds, bacterial pullulation), influence of several diseases (of urogynecologic, parasitic, general, dermatologic and psychogenic origin) and the particularly rich network of free nervous endings in this area give a good explanation for this frequent localisation of pruritis. |
