par Thomas, René 
Référence The International journal of developmental biology, 42, 3, page (479-485)
Publication Publié, 1998
Référence The International journal of developmental biology, 42, 3, page (479-485)
Publication Publié, 1998
Article révisé par les pairs
| Résumé : | We start our analysis from historical but too seldom quoted papers by Delbruck, Noveck and Weiner, Cohn and Horibata and Monod and Jacob. We try to show how it became possible to draw a line coupling cell differentiation to the physical concept of multistationarity, and the latter to the concept of positive feedback circuits. Two laws give the minimal logical ingradients required for differentiative and homeostatic regualtions. It is briefly shown how they can be used to treat such complex dynamics as deterministsic chaos, which, admittedly, does not yet belong to the corpus of developmental biology. It was taken as a challenge to express our ideas here in purely verbal terms, avoiding any formal treatment. |
