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Results of microsurgical epididymal sperm aspiration (MESA) and testicular sperm extraction (TESE) in azoospermic men using intracytoplasmic sperm injection (ICSI)

par Ubaldi, Filippo;Camus, Marguerite ;Tournaye, Herman;Clasen, Koen;Nagy, Z.;Smitz, J.;Van Steirteghem, André;Devroey, Paul
Référence Andrologia, 28, SUPPL. 1, page (71-75)
Publication Publié, 1996

Article révisé par les pairs

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Résumé :

The rationale and results of using epididymal and testicular spermatozoa with intracytoplasmic sperm injection (ICSI) for azoospermic patients are reviewed. A total of 128 consecutive ICSI/MESA cycles and a total of 120 consecutive ICSI/TESE cycles were performed up to December 1994. The two-pronuclei fertilization rate per intact oocyte (observed after the injection) was 58% and 60%, respectively, when epididymal and testicular spermatozoa were used. The embryo transfer rate was similar for the two procedures (91% after ICSI/MESA and 90% after ICSI/TESE). Fifty women became pregnant (positive HCG) when epididymal spermatozoa were used (39% per cycle and 43% per embryo transfer). Similar results were observed in the group of patients undergoing ICSI using testicular spermatozoa (36% per cycle and 40% per embryo transfer). These results are comparable to those obtained when ejaculated spermatozoa are used.